SKIN SCIENCE

The Science of Harmony: Healing Without Injury

Close-up of a spoon with creamy substance and small droplets on a white background

Our approach is to heal and regenerate the skin without causing inflammation. 

Researching the science behind common clinical skin rejuvenation strategies, we learned that these strategies induced ‘controlled inflammation’ - an immune system response to injury

Sapelo developed a 2-step regimen that replicates this response but without the resulting inflammation. 

Microneedling, microdermabrasion, chemical peels, lasers, RF therapy and retinoids create controlled inflammation which initiates an immune system response in your skin. This response is your body’s natural healing mechanism. The result: your body releases a prolific cascade of healing molecules to repair the injury sustained by your skin...  

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Proven results

WITH 2 SIMPLE STEPS

Renewing Serum + Rejuvenating Cream -  twice daily regimen that reduces inflammation and accelerates healing. 

Skin has an enormous capacity to repair, but that capacity is not unlimited. Chronic inflammation accelerates the decline in the skin’s ability to regenerate. Sapelo stops inflammaging by working with nature to promote healthy reproduction of skin cells. Our system penetrates deep into the dermis, working with daughter cells, to reduce stress on your skin’s recovery from the intrinsic and extrinsic forces on aging. The regimen stimulates the metabolic activity of the daughter cells to become more prolific – your skin is plumper, thicker and glowing – the true features of healthy skin. Used twice daily, your complexion will experience sustained optimal health and appearance. 

Reduce Inflammation and Accelerate Rejuvenation

We recognize the temporary improvements that come from harsh retinoids and resurfacing procedures, but we believe in a better way. Our unique technology harnesses your body's natural ability to repair and rejuvenate—without causing damage and inflammation to your delicate skin. We gently infuse your complexion daily with the same bioactive peptides, vitamins, and healing molecules your immune system produces in response to injury. This approach allows your skin to be continually stimulated to heal, renew, and look beautiful every day, making Sapelo the perfect, non-irritating ritual for lasting skin health.

sapelo skin care science

High Concentration, Clinically Effective Ingredients

Developed in Savannah, Georgia, our small-batch skincare is guided by physicians and scientists committed to gentle, effective rejuvenation. We merge contemporary research with traditional Southern remedies, using the highest concentration of clinically proven ingredients available. Our formulas feature high-quality botanical extracts and powerful cell-communicating peptides. Instead of causing harm, our system is scientifically designed to mimic the body's natural healing process, stimulating the production of collagen and elastin for improved skin density and a renewed, younger appearance.

Sapelo Skin Care Values

Our systems are developed under the guidance of board-certified physicians and veteran cosmetic scientists to ensure professional-grade results.

We believe skincare should work with the body, not against it. While the industry often relies on "controlled injury" through harsh acids and lasers, Sapelo honors the skin’s innate wisdom. By replicating the body’s natural immune response, we stimulate deep cellular regeneration without the trauma of inflammation.

No Acids or Retinoids: We eliminate the "burn" to prevent barrier depletion.

True luxury is found at the intersection of clinical science and cellular health. We combine high-concentration biomimetic peptides with the latest breakthroughs in molecular biology to deliver professional-grade results. Our formulations are engineered to stimulate deep regeneration while strictly preserving the integrity of the skin barrier for lifelong vitality.

Skin health is achieved through consistency, not trauma. Our formulations provide a targeted surge of bioactive ingredients designed to stabilize the skin’s environment and prevent the cycle of chronic inflammation. By prioritizing intentional, science-based care, we move beyond the "quick fix" to deliver lasting, visible transformation.

LOVE YOUR RESURFACING TREATMENTS?

POST TREATMENT

Sapelo is the perfect partner for post-clinical healing and correcting. Our products provide the ideal environment for your skin to thrive. Formulated by a renowned chemist and a team of physicians, Sapelo shortens the healing interval of clinical treatments and reduces the inflammatory response. Disciplined and prolonged use continues to trigger the immune system response cascade to ensure sustained, optimal health and the youthful appearance of skin.