Sapelo challenges the dogma of contemporary skin care solutions which claim retinols and hydroxyl acids are the gold standard for skin regeneration and anti-aging.

Retinols, hydroxyl acid, lasers, dermabrasions and acid peels, all work by injuring skin to create acute and chronic inflammation. Inflammation is a biological response to harmful and damaging stimuli that causes cellular injury. 

Our body’s immune system responds to this damage by releasing a cascade of healing cytokines and other essential molecules. Cytokines (a type of peptide) rush to aid the body by replacing the injured collagen, elastin, and skin cells. Inflammation also creates low grade edema or swelling which makes wrinkles temporarily disappear.

Daily application of caustic acids and the habitual use of injurious dermatological procedures accelerates aging and speeds up the moment when skin cells enter their senile phase and exhaust their capacity to repair.

 It isn’t anti-aging – it is accelerating aging.

This section doesn’t currently include any content. Add content to this section using the sidebar.



At Sapelo, we acknowledge the short-term improvement to skin after injurous procedues and acids, and we embrace the body's natural ability to repair. Our unique technology embraces this capacity for rejuvenation without first damaging our delicate complexions. 

Developed under the guidance of board-certified physicians and skilled veteran cosmetic scientists, Sapelo is the only skin care system that accurately replicates the body’s immune response and works in harmony with the body’s regenerative power.

Our products infuse the same bioactive peptides, vitamins, minerals, and other healing molecules, which are produced by our immune system in response to injury. Skin is daily stimulated to gently renew. And, for those women who chose to continue dermabrasion, micro-needling or chemical peels, Sapelo Skin Care is the perfect daily ritual to gently prolong the rejuvenating benefits.